Osteoporosis (OP) is a major public health concern that is both treatable and preventable. Thirty percent of men over fifty will sustain a fracture attributable to OP (Melton et al, 1992). However, most of what is known about OP is derived from research of post-menopausal women and men with prostate cancer who are treated with anti-androgen medications (Papaioannou, 2009). This study will examine the incidence and course of OP in men treated with anti-androgen medications due to a psychiatric disorder: pedophilia. This is important because a) it will allow an investigation of the prevalence of OP in men across a wide age range (18-80) with a variety of risk factors, b) it will permit an investigation of the risk of OP in the study samples using a variety of anti-androgen medications, and c) it will provide data on the efficacy of a variety of treatments for OP.
Investigators: Rebekah Ranger, Paul Fedoroff, John Bradford