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Director, Mood Disorders Research Unit
Studying the mechanisms of action of pharmacological medications (old, new, and experimental ones) in order to get patients with mood and/or anxiety disorders better faster. This is achieved by carrying out experiments in the basic research laboratory and applying the knowledge in the clinic.
Full professor in the departments of Psychiatry and Cellular & Molecular Medicine at the University of Ottawa; full medical privileges at The Royal Ottawa Mental Health Care Center; adjunct professor, department of Psychiatry, McGill University.
One of several key achievements: first clinician in Canada to use low doses of intravenous Ketamine to treat patients with severe major depressive disorder and co-author of two of the three publications that led to the worldwide approval of intranasal Esketamine as add-on treatment for resistant depression.
My research has helped to devise pharmacological strategies to obtain antidepressant responses in patients who had not benefited from even multiple trials. This has been achieved by documenting how medications work in the brain and subsequently applying this knowledge for rational prescribing. Prior publications from my clinical research and ongoing collaborative work with Canadian colleagues show that we can get faster responses by combining medications based on mechanistic foundations than using a single one. Such results turn hopeless treatment-resistant patients with mood and/or anxiety disorders into hopeful and future oriented individuals.
1145 Carling Ave.,
Ottawa, ON K1Z 7K4
(613) 722-6521
1141 Carling Ave.,
Ottawa, ON K1Z 7K4
(613) 722-6521
1804 Highway 2 E, P.O. Box 1050,
Brockville, ON K6V 5W7
(613) 345-1461
2121 Carling Ave.,
Ottawa, ON K2A 1H2
(613) 722-6521
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