Effects of electroconvulsive therapy on brain activity during sleep in late-life depression

People with depression often have sleep difficulties. Previous studies have showed that electroconvulsive therapy (ECT) can attenuate some of the sleep difficulties related to depression. However, little is known about how sleep may change with reductions in depressive symptoms after ECT. The present study evaluates the effects of ECT on brain activity during sleep in elderly persons with depression.

Age range

60 years and older



Individuals are eligible if they

  • Are referred to the ECT service at the Royal Ottawa Mental Health Centre;
  • Have a current diagnosis of a mood disorder;
  • Are able to provide informed consent

Individuals are not eligible if they

  • Have a lifetime diagnosis of schizophrenia, schizoaffective disorder, or intellectual disability;
  • Have a current diagnosis of any neurodegenerative illness (this does not include Mild Cognitive Impairment);
  • Have a current diagnosis of another neurological condition (such as epilepsy);
  • Have a major medical illness that could be an underlying factor for mood and/or sleep disorders;
  • Have had an active substance dependence within the last six months;
  • Have a history of head injury or loss of consciousness for more than 30 minutes;
  • Have undergone ECT treatment within the last two months


The Royal's Institute of Mental Health Research, affiliated with the University of Ottawa
Sleep Research Unit
1145 Carling Ave, Ottawa, ON

Recruitment Via

  • Internal Referral

Principal Investigators

Lisa McMurray, MD and Rébecca Robillard, PhD


Laura Ray
+1 (613) 722-6521 ext. 6544

*This study is currently recruiting participants